EFFECTS OF THYROID HORMONE
ON TARGET TISSUES
MOST EFFECTS OF THYROID HORMONE ARE ³PERMISSIVE²:
THYROID HORMONE PROMOTES SYNTHESIS OF PROTEINS WHICH ARE THEN
REGULATED ACUTELY BY OTHER
HORMONES.
GROWTH AND
DEVELOPMENT
THYROID HORMONE REQUIRED IN
PERINATAL PERIOD FOR:
NEURAL DEVELOPMENT
BONE GROWTH (GH)
THYROID
DISEASES
METABOLISM
THYROID HORMONE
INCREASES: BASAL METABOLIC RATE
BODY TEMPERATURE
CARDIAC OUTPUT/
TACHYCARDIA
MOBILIZATION OF ENERGY
STORES
CONGENITAL HYPOTHYROIDISM
DUE TO ³METABOLIC² DEFECT
IN THYROID HORMONE SYNTHESIS RESULTING IN MENTAL
RETARDATION
UNCOMMON IN DEVELOPED
COUNTRIES DUE TO EARLY POST- NATAL
TESTING
HYPERTHYROIDISM
AUTOIMMUNE ³GRAVES DISEASE²
PITUITARY TUMOR
THYROID TUMOR
WEIGHT LOSS
³ENDEMIC²
HYPOTHYROIDISM
DUE TO IODIDE DEFICENCY OR GOITROGENS.
READILY PREVENTED BY IODIDE SUPPLEMENTATION OF FOOD