PowerPoint Presentation - Low Lectures

Thyroglobulin

I

I

Tyr

3,5,3ą5ą-tetraiodothyronine

I

I

Tyr

I

I

I

Tyr

O

T

CH2CHCOOH

I

I

I

Tyr

NH2

+

NH2

I

4

I

I

Tyr

CH2CHCOOH

NH2

CH2CHCOOH

3,3ą,5ą-Triiodothyronine (reverse T3)

NH2

Tyr

I

I

I

Tyr

O

rT3

I

3,5,3ą-Triiodothyronine (T3)

I

I

Tyr

I

I

I

Tyr

O

T4

I

T3

Tyr

I

I

I

Tyr

O

I

5ą- deiodination

5-deiodination

CH2CHCOOH

łACTIVATION˛ PATHWAY

łDEACTIVATION˛ PATHWAY

NH2

STEP 3 DEIODINATION

SELENODEIODINASES